Clinical Research

Clinical Research

About Our Research

Our FDA-backed clinical research program plays a pivotal role in enhancing the well-being of our patients. Over the years, we have been actively engaged in numerous innovative trials focused on various retinal diseases. Through our dedicated involvement, we have contributed significantly to the progress of treatment for diseases such as Diabetic Macular Edema, Diabetic Retinopathy, and Age-Related Macular Degeneration. This participation enables us to offer our patients early access to groundbreaking treatment options, instilling hope for a healthier future. Additionally, many of our trials offer care at no cost to the patient (regardless of insurance status or type) and often include other benefits such as paid transportation.  All of our Retina Specialist M.D.s are closely engaged in our clinical trials and we have a specially-trained research staff to optimize our patients’ experience.  With each trial, we deepen our understanding of eye diseases, bringing us closer to the ultimate goal of eradicating blindness.

If you are interested in determining your eligibility for a trial, please contact our Clinical Research Coordinator at (503) 296-6484.

Ongoing Clinical Trials

Age-Related Macular Degeneration

A Multicenter, Prospective, Observational Study of the Progression of Intermediate Age-Related Macular Degeneration

A Phase 2, Double-Masked, Placebo-Controlled, Dose Range Finding Study of Danicopan (ALXN2040) in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)

A Phase 3, Multicentre, Double-masked, Randomised Study to Evaluate the Efficacy and Safety of Intravitreal OPT-302 in Combination With Ranibizumab, Compared With Ranibizumab Alone, in Participants With nAMD

A Phase 3, Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Pegcetacoplan in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration

An Open-label Extension (OLE) Phase 3 Trial to Assess the Safety of Intravitreal Administration of Avacincaptad Pegol (Complement C5 Inhibitor) in Patients With Geographic Atrophy Who Previously Completed Phase 3 Study ISEE2008 (GATHER2)

A Phase 2, Multicenter, Randomized, Double-Masked, Parallel Group Study to Assess the Efficacy and Safety of KHK4951, a Vascular Endothelial Growth Factor Receptor Inhibitor, in Patients With Neovascular Age-Related Macular Degeneration.


Diabetic Retinopathy & Diabetic Macular Edema

A Phase II, Multicenter, Randomized, Double Masked, Active Comparator-Controlled Study to Investigate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7200220 Administered Intravitreally in Patients With Diabetic Macular Edema

A Phase 2b, Prospective, Multicenter, Randomized, Double-Masked, Active-Controlled Study to Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With Diabetic Macular Edema

A Randomized, Double-Masked, Active-Controlled Phase 2/3 Study of the Efficacy and Safety of High-Dose Aflibercept in Patients With Diabetic Macular Edema

A Phase 2, Multicenter, Randomized, Double-Masked, Parallel-Group Study to Assess the Efficacy and Safety of KHK4951, a Vascular Endothelial Growth Factor Receptor Inhibitor, in Patients With Diabetic Macular Edema


Past Trials

A Randomized, Double-Masked, 48-Week, Parallel-Group, Placebo-Controlled, Proof-of-Concept Study to Investigate the Efficacy and Safety of RG7774 in Patients With Diabetes Mellitus Type 1 or Type 2 With Treatment-Naive Diabetic Retinopathy

A Phase 2a, Prospective, Multicenter, Randomized, Double Masked, Sham-Controlled Study to Assess the Safety, Tolerability and Evidence of Activity of a Single Intravitreal Injection of UBX1325 in Patients With Diabetic Macular Edema

A Phase 3, Multi-Center, Randomized, Double-Masked, Sham-Controlled Study to Compare the Efficacy and Safety of Intravitreal Pegcetacoplan Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)

A Phase 2, Prospective, Multicenter, Randomized, Double-Masked, Active-Controlled Study to Assess the Safety, Tolerability, and Evidence of Activity of a Repeat Intravitreal Injection of UBX1325 in Patients With Neovascular Age-Related Macular Degeneration (Wet AMD)

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Our Locations

Aloha
18345 SW Alexander St,
Suite A
Aloha, OR 97003
(503) 642-2505 see more
Glisan
6701 NE Glisan Street
Portland, OR 97213
(503) 255-2291 see more
Gresham
24601 SE Stark St.
Suite 245
Troutdale, OR 97060
(503) 255-2291 see more
Hillsboro
6111 NE Cornell Rd
Hillsboro, OR 97124
(503) 846-9400 see more
Lake Oswego
9 Monroe Parkway, Suite 160
Lake Oswego, OR 97035
(503) 636-2551 see more
Milwaukie
11086 SE Oak St
Milwaukie, OR 97222
(503) 656-4221 see more
Mt. Tabor
5935 SE Division St.
Portland, OR 97206
503 777-5546 see more
Newberg
2318 Portland Rd, Suite 300
Newberg, OR 97132
(503) 538-1341 see more
North Portland
3246 N. Lombard St.
Portland, OR 97217
(503) 285-1671 see more
Northwest Portland
1955 NW Northrup St
Portland, OR 97209
(503) 227-2020 see more
Oregon City
1306 Division St
Oregon City, OR 97045
(503) 656-4221 see more
Peterkort
9555 SW Barnes Rd.
#100 (1rst floor)
Portland, OR 97225
(503) 227-2020 see more
Providence Portland
5050 NE Hoyt St., Suite 445
Portland, OR 97213
(503) 231-0166 see more
Providence St. Vincent
9135 SW Barnes Rd., Suite 961
Portland, OR 97225
(503) 292-0848 see more
Southeast Portland
10819 SE Stark St,
Portland, OR 97216
(503) 255-2291 see more
Sunnyside
12050 SE Stevens Rd, Suite 100
Happy Valley, OR 97086
(503) 783-3300 see more
Tigard
15298 SW Royalty Parkway
Tigard OR 97224
(503) 227-2020 see more
Wilsonville
29250 SW Town Center Loop W
Wilsonville, OR 97070
(503) 582-0000 see more
Westside Surgery Center
13240 SW Pacific Hwy
Portland, OR 97223
(503) 639-6571 see more
EyeHealth Eastside Surgery and Laser Center
12050 SE Stevens Rd.
Happy Valley, OR 97086
(971) 206-6100 see more

Our Locations

Aloha
18345 SW Alexander St,
Suite A
Aloha, OR 97003
(503) 642-2505 see more
Glisan
6701 NE Glisan Street
Portland, OR 97213
(503) 255-2291 see more
Gresham
24601 SE Stark St.
Suite 245
Troutdale, OR 97060
(503) 255-2291 see more
Hillsboro
6111 NE Cornell Rd
Hillsboro, OR 97124
(503) 846-9400 see more
Lake Oswego
9 Monroe Parkway, Suite 160
Lake Oswego, OR 97035
(503) 636-2551 see more
Milwaukie
11086 SE Oak St
Milwaukie, OR 97222
(503) 656-4221 see more
Mt. Tabor
5935 SE Division St.
Portland, OR 97206
503 777-5546 see more
Newberg
2318 Portland Rd, Suite 300
Newberg, OR 97132
(503) 538-1341 see more
North Portland
3246 N. Lombard St.
Portland, OR 97217
(503) 285-1671 see more
Northwest Portland
1955 NW Northrup St
Portland, OR 97209
(503) 227-2020 see more
Oregon City
1306 Division St
Oregon City, OR 97045
(503) 656-4221 see more
Peterkort
9555 SW Barnes Rd.
#100 (1rst floor)
Portland, OR 97225
(503) 227-2020 see more
Providence Portland
5050 NE Hoyt St., Suite 445
Portland, OR 97213
(503) 231-0166 see more
Providence St. Vincent
9135 SW Barnes Rd., Suite 961
Portland, OR 97225
(503) 292-0848 see more
Southeast Portland
10819 SE Stark St,
Portland, OR 97216
(503) 255-2291 see more
Sunnyside
12050 SE Stevens Rd, Suite 100
Happy Valley, OR 97086
(503) 783-3300 see more
Tigard
15298 SW Royalty Parkway
Tigard OR 97224
(503) 227-2020 see more
Wilsonville
29250 SW Town Center Loop W
Wilsonville, OR 97070
(503) 582-0000 see more
Surgery Centers

Westside Surgery Center

13240 SW Pacific Hwy
Portland, OR 97223
(503) 639-6571 see more

EyeHealth Eastside Surgery and Laser Center

12050 SE Stevens Rd.
Happy Valley, OR 97086
(971) 206-6100 see more